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Check Out Discovery's 2024 Year-End Sales Event NEW Tumoroid Cell Lines are Now Available NEW Lunaphore COMET Hyperplex IF Services Innovative Metabolic Co-Culture Hematotoxicity CFC Assay Services

Check Out Discovery's 2024 Year-End Sales Event NEW Tumoroid Cell Lines are Now Available NEW Lunaphore COMET Hyperplex IF Services Innovative Metabolic Co-Culture Hematotoxicity CFC Assay Services

Gentest^® Myeloid and Erythroid Cell Maturation Assay Services

Assess neutropenia or severe anemia caused by drug candidate toxicity to neutrophils and red blood cells at various stages of cell development.

While myeloid and erythroid colony forming cell (CFC) assays are predictive of neutropenia and severe anemia caused by drugs impacting the primitive progenitor stage, toxicity can also occur at later stages of cell development.

Discovery’s myeloid and erythroid cell maturation assay services further assess the off-target toxicity potential of your drug candidate on developing neutrophils and red blood cells at different stages of cell development.

Predict drug candidate toxicity to developing neutrophils and red blood cells
Use primary CD34+ cells cultured with specific growth factors to induce myeloid or erythroid lineage differentiation
Adapt to your needs-liquid culture allows for drug administration and/or washing out at multiple timepoints, simulating clinical treatment options
Track neutrophil and red blood cell development and drug interference using flow cytometry
Deepen toxicity understanding with biologically relevant data

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