Recent advances in high-throughput proteomics have greatly enhanced biomarker discovery by improving the ability to identify and characterize biomarkers, creating new opportunities for understanding.
The success of biomarker discovery efforts depends not only on technological capabilities but also on rigorous cohort design, standardized sample handling, high-quality data generation and scalable informatics solutions.
This webinar will present an integrated approach that combines minimally invasive plasma proteomics with tissue-based proteogenomic analysis to explore the molecular foundations of disease. Specifically, the speaker will discuss the profiling of 500 plasma samples using two complementary high-throughput platforms — mass spectrometry and Olink — and the analysis of matched formalin-fixed paraffin-embedded (FFPE) tissue from a subset of participants through integrated proteomic and genomic workflows.