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Allergy and Inflammation Solutions

Discovery offers highly functional primary human mast cells and in vitro mast cell culture services to evaluate immune cell responses as well as high-throughput Olink^® Target panels for inflammatory biomarker profiling.

Primary Human Mast Cells

High-Quality. Biologically Relevant. Ready-to-Use.

Discovery’s primary human mast cells are fresh, ready-to-use, and validated through degranulation assays by our expert cell biologists. Fully characterized and biologically relevant, these mast cells offer high viability, immediate functionality, and reproducibility to generate relevant data.

Allergic Reaction Testing: Analyze a drug candidate’s effects on mast cell degranulation and histamine release to help assess potential for reducing allergic responses in patients.
Drug Screening: Evaluate the efficacy of compounds in reducing mast cell activation as an indicator of immune modulation.

Mast Cell Culture and Assay Services

Functional mast cell assays for allergy drug discovery and immune modulation.

Leverage Discovery’s deep expertise in mast cell biology to evaluate your compound of interest. Our cell biology lab offers mast cell culture, cell degranulation, histamine release, and activation assay services to support your allergy and inflammation research.

Olink Target Services

High-throughput protein biomarker profiling for inflammation & allergy research.

As an Olink-certified service provider, Discovery’s proteomics lab offers a range of Olink Target services designed for allergy and inflammation studies. Choose from the new Reveal Panel, Target 96 Inflammation Panel, Target 48 Cytokine and Immune Surveillance Panels, or explore customizable Flex and Focus options.

Frequently Asked Questions

What is the optimal time to perform mast cells assays?

Mast cell assays should be performed 1 – 2 days following passaging. The differences in CD63 expression (a marker for degranulation) between the non-stimulated controls and activated mast cells will be optimal at this time. Consult with a Discovery cell biologist for detail.

How are the mast cells derived?

They are derived from Discovery's AllCells® healthy donor mobilized peripheral blood CD34+ cells.

What is the lead time for receiving mast cells?

1 to 7 weeks.

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Allergy and Inflammation Solutions

Primary Human Mast Cells

High-Quality. Biologically Relevant. Ready-to-Use.

Mast Cell Culture and Assay Services

Functional mast cell assays for allergy drug discovery and immune modulation.

Olink Target Services

Frequently Asked Questions

Contact Us Today

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