Single-Cell Genomics Services
Backed by deep expertise in cell biology, assay design, and sample preparation, we match every project with the right single-cell technology to maximize biological insight and overall value. As an official certified service provider for both 10x Genomics and Parse Biosciences, we help researchers select the optimal single-cell platform(s) based on their scientific objectives.
Expert Cell Biology. High-Quality Libraries. Unmatched Single-Cell Insights.
No two studies are the same. Discovery’s cell biology experts evaluate sample count, cell numbers, sequencing depth, and experimental design to identify the best approach for your project.
Optimized Sample Quality Assessment
- Fluorometry-based evaluation to ensure high-quality starting materials
- Flow cytometry to guide antibody-directed barcoding for CITE-Seq
Comprehensive Sample Preparation
- Supports diverse sample types, including whole blood, bone marrow, fresh, frozen tissue, and FFPE
- Streamlined processing under one roof to minimize transfer times
Efficient Cell Isolation and Cleanup
- Dead cell removal and cell population isolation before library prep
- Advanced magnetic bead isolation methods
In-Process Quality Control
- Real-time quality assessments during key processing steps
- Ensures optimal sample integrity before sequencing
High-Quality Library Construction
- Size selection and cleanup to remove unbound or nonspecific probes
- Meticulous quality and quantity checks to meet sequencing specs
Expert Bioinformatics Analysis
- Comprehensive analysis evaluating library prep and tissue quality
- Clear, actionable, and data-driven presentations delivered to clients
Single-Cell Sequencing Example Readouts
CITE-Seq Example Readout
ATAC-Seq Example Readout
Frequently Asked Questions
We offer various types of single-cell sequencing services:
- scRNA-seq or Single-Cell Gene Expression
- scVDJ-seq or Single-Cell Immune Profiling
- scATAC-seq or Single-Cell Chromatin Accessibility
- Single-Cell ATAC and Gene Expression
- Single-Cell Copy Number Variation
- CITE-seq or Single-Cell Feature Barcoding
- Single-Cell CRISPR Screening
These platforms are optimized for different research goals. Rather than a one-size-fits-all approach, they provide complementary benefits that help researchers choose the best solution for their study design, sample types, and scale.
10x Genomics:
- High-confidence cell type and cell state characterization
- Widely adopted, well-established workflows with extensive community support
- Multi-omic profiling from the same cell (e.g., gene expression, chromatin accessibility, and protein)
- Deep characterization of complex tissues and rare cell populations
- Cell surface protein analysis alongside gene expression
- Chromatin accessibility and gene regulatory studies
- CRISPR perturbation screening with integrated molecular readouts
Parse Biosciences:
- Large-scale studies involving hundreds of samples
- Profiling very large numbers of cells cost-effectively
- Longitudinal studies with multiple collection time points
- Multi-site and clinical research programs
- Minimizing batch effects through sample multiplexing
- Flexible sample collection and processing timelines
- Scaling studies efficiently while managing costs
Ebook
From Sample to Signal - Integrated Genomics for Smarter Therapeutic Development
Learn about Discovery’s reliable, scalable, and
customizable genomics solutions that support
both preclinical and clinical development
programs.
