White Paper - Companion Diagnostic Development: An Overview Improving Pathology Precision in Oncology: How AI Reduces Variability in Tumor Percent Assignments NEW Gentest Cryopreserved Plateable Mouse Hepatocytes are Now Available

Gentest^®Megakaryocyte Maturation and Platelet Development Assay Services

Assess thrombocytopenia potential caused by drug candidate toxicity to megakaryocytes and platelets at various stages of development.

While Megakaryocytic colony forming cell (CFC) assays are predictive of thrombocytopenia caused by drugs impacting the primitive progenitor stage, toxicity can also occur at later stages of cell development.

Discovery’s megakaryocyte maturation and platelet development assay services assess the off-target toxicity potential of your drug candidate on developing megakaryocytes and megakaryocyte-derived platelets at different stages of cell development.

Predict drug candidate toxicity to developing megakaryocytes and platelets
Use primary CD34+ cells cultured with specific growth factors to induce megakaryocytic lineage differentiation
Adapt to your needs-liquid culture allows for drug administration and/or washing out at multiple timepoints, simulating clinical treatment options
Track megakaryocytic development and drug interference using flow cytometry
Deepen toxicity understanding with biologically relevant data

Contact Us Today

Privacy Settings

Gentest® Megakaryocyte Maturation and Platelet Development Assay Services

While Megakaryocytic colony forming cell (CFC) assays are predictive of thrombocytopenia caused by drugs impacting the primitive progenitor stage, toxicity can also occur at later stages of cell development.

Contact Us Today

Gentest Services

MARKETS WE SERVE

COMPANY

Markets We Serve

Resources

Popular Keywords

Categories,Pages

Quick Links

Technologies

Development and Clinical Trial Solutions

Our Mission

Technologies

Development and ClinicalTrial Solutions

Post-Approval Services

Gentest^®Megakaryocyte Maturation and Platelet Development Assay Services

Development and Clinical
Trial Solutions

Development and Clinical
Trial Solutions