Join us at Phacilitate Advanced Therapy Week in Dallas Advance CGT Programs from RUO to GMP with AllCells^® Solutions Discovery's Molecular Pathology Team Contributed to Recent GDF-15 Study on Nature

Join us at Phacilitate Advanced Therapy Week in Dallas Advance CGT Programs from RUO to GMP with AllCells® Solutions Discovery's Molecular Pathology Team Contributed to Recent GDF-15 Study on Nature

TruSight™ Oncology 500 (TSO500)

Streamlined Parallel Histopathology and NGS Workflows to Detect Clinically Relevant DNA and RNA Variants in Various Solid Tumor Indications

Discovery Genomics' TSO500 Solid Tumor NGS service provides high sensitivity detection of genomic variants across 523 DNA genes and 55 RNA fusion events in most major cancer indications and sample types, including microsatellite instability (MSI) and tumor mutational burden (TMB).

Applications

Our TSO500 NGS services provide pan-cancer genomic biomarker analysis of SNVs, InDels, CNVs, Fusions, TMB, and MSI to enable:

Discovery and verification of the presence of genomic biomarker targets and signatures in solid tumors
Retrospective identification of potential oncology clinical trial patient responders versus non-responders based on genomic profiles
RUO development and orthogonal validation of novel solid tumor diagnostic solutions
Combine the matching TSO500 Solid Tumor and TSO500 ctDNA applications to develop and validate non-invasive liquid biopsy assays from matched-patient Plasma and FFPE samples

Service Performance Data

Using commercially available reference standards in our optimized and automated nucleic acid extraction, library construction, and sequencing workflows, we demonstrate the accuracy, sensitivity, and reproducibility of our TSO500 ctDNA NGS service

ACCURACY:

>99%

LIMIT OF DETECTION:

> 2% Allele Fractions

Reproducability:

>97%

TSO500 Solid Tumor NGS Services Deliverables

TSO500HT v2.2 Output files

DNA Results

RNA Results

Combined DNA + RNA Results

QC and Metrics Files

Sample Input Requirements

Related Products & Services

FFPE and Other Oncology Specimens

Optimized Dual DNA/RNA Extraction Services

Molecular Pathology Services

TSO500 Liquid Biopsy
NGS Services

Other Sequencing
Services

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