High-Throughput RNA Sequencing Services for Comprehensive Transcriptomic Insights

Discovery offers multiple RNA sequencing formats including low-input mRNA-Seq, dual RNA/DNA extraction, stranded total RNA-Seq, and customized pipelines for FFPE or fresh frozen samples. We tailor workflows to match your sample type and research goals.

Yes. Our optimized RNA-Seq workflow is specifically designed to accommodate degraded RNA from FFPE samples, with validated protocols that minimize dropout and preserve transcriptome integrity.

Our average turnaround time is approximately 2–4 weeks, depending on project complexity, sample quality, and bioinformatics requirements. Expedited options are available upon request.

You will receive FASTQ files, optional BAM alignment files, expression count matrices, and QC metrics. We also offer optional bioinformatics reports including differential gene expression, clustering, and pathway analysis.

Yes. Our scientific team provides upfront consultation on library prep method, input quantity, read depth, and bioinformatics endpoints to ensure your RNA-Seq experiment aligns with your goals.

We can accept as little as 10 ng of total RNA from high-quality samples and have protocols for degraded RNA inputs from FFPE down to DV200 ≥30%. For best results, we recommend ≥100 ng of total RNA.

Contact us at info@dls.com or click here and we will put you in touch with the right experts to discuss your project.

A Scope of Work (SOW) and/or Purchase Order (PO) must be completed before arranging any sample shipment. Shipments received prior to receipt of proper information will be quarantined and may be returned to the sender if needed information and official documentation is not received in a timely manner. It is suggested that a project kick-off discussion be conducted prior to shipment of any samples to ensure alignment with the laboratory activities upon receipt of samples.

An Analytical Plan will be compiled by your dedicated project manager. The Analytical Plan details laboratory activities and ensures client alignment prior to any sample processing.

The Analytical Plan will be shared with you for edits and comments. Discovery’s quality standards require that the Analytical Plan is agreed upon and signed off by Discovery and the client prior to any testing being performed.

Your primary contact throughout your project will be your dedicated project manager.

NOTE: Some projects may not require a formal Analytical Plan if deemed out of scope for the nature of the project at Discovery's discretion. This will be discussed with your Project Manager during the initiation of each project.

All sample shipments will require a clearly defined manifest including Protocol/Study identification, sample information, patient ID (if available), and contact information for shipper to rectify missing and/or ambiguous information.

Click here to see sample shipment requirements.

Any shipments missing this critical information will be put into quarantine and may experience extended turnaround times.