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Induction of cytochrome P450 and UGT enzyme catalytic activity is a leading mechanism of metabolism-based drug-drug interactions.
In vitro induction studies are valuable predictors of in vivo drug-drug interactions. Gentest® Research Services utilizes high quality, highly characterized Gentest® human and animal hepatocytes, as well as chemicals and culture-ware to deliver robust, reproducible results.
The combination of proprietary products, advanced technology and expert guidance from experienced study directors provides clients with reliable, submission-ready results.