Spatial Biology Center of Excellence

By combining industry-leading expertise in spatial multiplex immunofluorescence (mIF), including hyperplex spatial profiling, and spatial transcriptomics, Discovery delivers comprehensive spatial insights that reveal the biological relationships driving disease and therapeutic response. 

 

Leading Expertise Across the Spatial Biology Continuum

From tissue architecture and protein expression to single-cell and subcellular gene expression, our integrated workflows provide the complete spatial biology toolkit for today’s most challenging research questions. 

Comprehensive Spatial Biology Services

Leverage a single partner for spatial protein and spatial transcriptomic analysis, supported by experienced pathologists, assay development scientists, cell biologists, and bioinformatics experts.

End-to-End Multi-Omics

Enable integration of spatial insights with complementary molecular and cellular data for a more complete understanding of disease biology, therapeutic response, and biomarker potential.

Clinical-Grade Quality & Regulatory Excellence

Advance translational research and clinical development with GCLP-compliant workflows, CLIA-certified and CAP-accredited laboratories, and globally harmonized testing capabilities that deliver reliable, reproducible results.

Access to Premium Biospecimens

Accelerate spatial biology studies with access to one of the world’s largest commercial biobanks and global clinical networks, enabling high-quality cohorts, rare specimen sourcing, and faster study execution. 

Discovery’s Spatial Biology Service Portfolio

Spatial Multiplex Immunofluorescence (mIF)

Visualize and quantify multiple protein biomarkers simultaneously while preserving tissue context. Discovery’s mIF experts combine custom assay development, GCLP-compliant workflows, advanced digital image analysis, and spatial phenotyping capabilities to deliver quantitative insights into immune cell populations, biomarker expression, and cell-to-cell interactions within the tissue microenvironment. 

For researchers requiring deeper profiling, Discovery leverages the Bio-Techne Spatial COMET™ Hyperplex IF platform to measure up to 40 markers from a single tissue section with subcellular resolution, enabling deep immunophenotyping, comprehensive tumor microenvironment characterization, and multidimensional spatial analysis. Together, these capabilities provide scalable mIF solutions that transform precious tissue samples into actionable biological insights. 

Spatial Transcriptomics

As a certified 10x Genomics Visium and Xenium service provider, our cell biology experts perform single-cell and subcellular gene expression analysis within the context of intact tissue morphology. Discovery combines specialized tissue preparation, spatial transcriptomics expertise, and advanced analytics to reveal cellular organization, spatial gene expression patterns, and novel biomarkers.

Spatial Biology Applications

Biomarker Discovery & Translational Research

Identify novel biomarkers and develop predictive signatures to support precision medicine strategies

Immuno-Oncology

Characterize immune infiltration, cell-cell interactions, and spatial biomarkers driving therapeutic response.

Oncology

Study tumor heterogeneity, tumor microenvironment architecture, and disease progression mechanisms. 

Immunology & Inflammation

Map immune cell populations and understand tissue-specific inflammatory processes.

 

 

Neuroscience

Explore cellular organization and molecular pathways within complex neural tissues.

Infectious Diseases

Investigate pathogen-host interactions and localized immune responses within tissue.  

Featured Resources

Establishing Quantitative Image Analysis Driven Multiplex Immunofluorescence Panels for Retrospective Clinical ResearchPoster

Research Use Only (RUO) Validation of ‘Off the Shelf’ Multiplex Immunofluorescence (mIF) Panels with Quantitative Image Analysis for use in Retrospective Clinical TrialsPoster

mIF and Image Analysis in Colorectal CancerPoster

Establishment of an Immune Cell Phenotyping Multiplexed Immunofluorescence Assay and Digital Image Analysis Workflow to Investigate the Tumor Microenvironment of Solid TumorsPoster

Multiplex Immunofluorescence (mIF) and Spatial Analysis Services One SheetOne Sheet

Bio-Techne Spatial COMET™ Hyperplex IF ServicesOne Sheet

Speak with Our Spatial Biology Expert

Whether you need tissue characterization, spatial protein profiling, single-cell transcriptomics, or a fully integrated spatial biology strategy, Discovery’s experts can help you identify the right technologies and design the optimal approach for your research goals. Complete the form below to connect with a spatial biology specialist. 

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