Colorectal and Lung Tumoroids are Now Available NEW Blog Post - Progressing Ex Vivo Gene Editing Innovations with High-Quality Leukopaks Learn More about Discovery's AI-Annotated FFPE Tissues and DiscoverAI Tissue Analysis NEW Blog Post - Improving Pathology Precision in Oncology: How AI Reduces Variability in Tumor Percent Assignments Discovery Announces Upcoming Launch of Tumoroids at Precision Med Tri-Con
Colorectal and Lung Tumoroids are Now Available NEW Blog Post - Progressing Ex Vivo Gene Editing Innovations with High-Quality Leukopaks Learn More about Discovery's AI-Annotated FFPE Tissues and DiscoverAI Tissue Analysis NEW Blog Post - Improving Pathology Precision in Oncology: How AI Reduces Variability in Tumor Percent Assignments Discovery Announces Upcoming Launch of Tumoroids at Precision Med Tri-Con
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Clinical Flow Cytometry Services

High-resolution spectral data at the single-cell level to support
global clinical trials with speed and scale.

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Our Clinical Flow Cytometry Services start with expert assay development and optimization and end with reliable data conducted in state-of-the-art service laboratories under relevant regulatory compliance (CLIA-certified, CAP-accredited, and GCLP compliant)

Discovery's Clinical Flow Cytometry Service Advantages

State of the Art Technologies

  • High-resolution spectral flow cytometry data at the single-cell level using Cytek® Aurora systems
  • Up to 40-markers simultaneously for comprehensive answers to critical questions

Expert Assay Development and Validation

  • Expert consultation to design custom panels and rigorously validate assays
  • Technology transfer of client developed custom panels

Customized Solutions for Clients

  • Approach every project like a partnership to foster trust and client retention
  • Dedicated expert scientific support and direct communications throughout every clinical trial project

Flexibility

  • We can start projects quickly and offer short timelines
  • Integrated capabilities to accelerate new assay development or technology transfer

Biospecimens and Multi-omics Services Under One Roof

  • Access to the largest, most characterized commercial biorepository for validation samples
  • Adjacent to genomics, proteomics, and molecular pathology service laboratories
  • Single chain of custody and optimized logistics

Clinical Flow Cytometry Services

Our experts have designed an industry-leading approach that starts with careful assay development and optimization to meet
CAP, CLIA and GCLP guidelines.

Custom Assay Development & Validation

  • Custom panel & assay design
  • Fit-for-purpose validation
  • Technology Transfer of client developed panels

Phenotyping / Immunoprofiling

  • TBNK enumeration
  • Lymphocytes (T cells, B cells, NK cells)
  • T cell activation / exhaustion
  • Monocyte/macrophage
  • MDSC & DCs

Target Engagement

  • Receptor occupancy: mAb, bi-specific Ab
  • Cell signaling & signal transduction
  • CAR-T

Immuno-oncology & Oncology

  • AML
  • MM
  • CLL
  • NHL
  • And more

Clinical Flow Cytometry Service Applications

  • Detect biomarkers across a broad range of normal and diseased samples
  • Comprehensive immunoprofiling of patient samples: up to 40 markers/colors simultaneously.
  • Develop custom assays to meet customer needs as well as ability to perform technology transfer of client-developed panels from similar or different platforms.
  • Assess target engagement, drug efficacy, receptor occupancy, and mechanism of action.
  • Testing of exploratory/retrospective (RUO) and prospective (CAP/CLIA) clinical trial patient samples
  • Understand targets in preclinical models and accelerate transition to the next stage of development
  • Advanced biomarker detection by flow cytometry with up to 40 markers measured simultaneously for custom assay development and tech transfer, and assessment of target engagement, drug efficacy, and mechanism of action in exploratory and clinical trial samples.

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